Lateral diffusion on fused cell doublets

Effect of Membrane Potential on Lateral Diffusion

The rate of appearance , in a populat ion of mouse-human heterokaryons , of cells with intermixed mouse and human surface antigens may be used to estimate the rate of lateral diffusion of the antigens in a single cell. Most he terokaryons appear to restrict diffusion of their surface antigens. These restrictions are altered by exposing either he terokaryons or their parent cells to conditions t...

Lateral Diffusion of Proteins in Cell Membrane: The Anomalous Case

We present a method describing the lateral movement of proteins in cell membranes as observed in FRAP experiments. We extend earlier results derived for normal diffusion [1] to account for the case of anomalous subdiffusion. Our analytic closed forms are compared to computer simulations of anomalous diffusion and both show excellent agreement. The approach sheds light on the behavior of protein...

Cell wall constrains lateral diffusion of plant plasma-membrane proteins.

A cell membrane can be considered a liquid-phase plane in which lipids and proteins theoretically are free to diffuse. Numerous reports, however, describe retarded diffusion of membrane proteins in animal cells. This anomalous diffusion results from a combination of structuring factors including protein-protein interactions, cytoskeleton corralling, and lipid organization into microdomains. In ...

Lateral Diffusion in Membranes

Diffusion rates of cell surface antigens of mouse-human heterokaryons. II. Effect of membrane potential on lateral diffusion

The rate of appearance, in a population of mouse-human heterokaryons, of cells with intermixed mouse and human surface antigens may be used to estimate the rate of lateral diffusion of the antigens in a single cell. Most heterokaryons appear to restrict diffusion of their surface antigens. These restrictions are altered by exposing either heterokaryons or their parent cells to conditions that c...